Regenerative Repair and Medicine

Stem Cells

Stem Cells:
Stem cells are multipotent cells are capable of both self-renewal and multi-lineage differentiation, including muscle cells. The term stem cell originated in the context of two main embryological questions of that time first one is the continuity of the germ-plasm and the origin of the hematopoietic system. Bone-marrow is derived stem cells, endothelial progenitor cells and unique stem cells from fat are the foremost widely used for implantation into the injured myocardium. It has originally hypothetical that stem cells implanted into the myocardial milieu would differentiate into cardio myocytes to exchange those lost during the myocardial infarct. The encouraging results of the preclinical studies triggered that variety of clinical trials. The first clinical trials established the utility of somatic cell therapy to repair the injured myocardium. Animal studies confirmed that somatic cell transplantation was safe and potentially efficacious.