Cell Therapy and Cryopreservation

Cell therapies with short shelf-life due to a “fresh” final product (as the product is not designed for a long-term storage) are perfectly acceptable for proof of concept of the cell therapy. But when it enters late-stage development and then commercial production, different constraints arise. Thus a cryopreserved final product becomes a necessity when considering the possibility of a late-stage clinical or commercial product with potentially thousands of doses a year that are needed to be shipped to different hospitals all over a continent or the world.

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